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New England Journal of Medicine-Data Study Semaglutide for Weight Loss:
ORIGINAL ARTICLE Once-Weekly Semaglutide in Adults with Overweight or Obesity List of authors. John P.H. Wilding, D.M., Rachel L. Batterham, M.B., B.S., Ph.D., Salvatore Calanna, Ph.D., Melanie Davies, M.D., Luc F. Van Gaal, M.D., Ph.D., Ildiko Lingvay, M.D., M.P.H., M.S.C.S., Barbara M. McGowan, M.D., Ph.D., Julio Rosenstock, M.D., Marie T.D. Tran, M.D., Ph.D., Thomas A. Wadden, Ph.D., Sean Wharton, M.D., Pharm.D., Koutaro Yokote, M.D., Ph.D., et al., for the STEP 1 Study Group Discussion In this trial, we found that adults with obesity (or overweight with one or more weight-related coexisting conditions) and without diabetes had a mean weight loss of 14.9% from baseline with semaglutide as an adjunct to lifestyle intervention. This loss exceeded that with placebo plus lifestyle intervention by 12.4 percentage points. The 14.9% mean weight loss that we observed in the semaglutide group is substantially greater than the weight loss of 4.0 to 10.9% from baseline with approved antiobesity medications.3,19 Moreover, 86% of participants who received semaglutide, as compared with 32% of those who received placebo, lost 5% or more of baseline body weight, a widely used criterion of clinically meaningful response.2,3,20,21 Weight loss with semaglutide stems from a reduction in energy intake owing to decreased appetite, which is thought to result from direct and indirect effects on the brain.22-25 Weight loss with semaglutide was accompanied by greater improvements than placebo with respect to cardiometabolic risk factors, including reductions in waist circumference, blood pressure, glycated hemoglobin levels, and lipid levels; a greater decrease from baseline in C-reactive protein, a marker of inflammation; and a greater proportion of participants with normoglycemia. Semaglutide also improved physical functioning, as assessed by SF-36 and IWQOL-Lite-CT, a finding that is notable given that overweight and obesity significantly impair health-related quality of life.26 Statistical superiority of semaglutide over placebo was achieved for all end points in the hierarchical testing procedure. Weight loss of 10 to 15% (or more) is recommended in people with many complications of overweight and obesity (e.g., prediabetes, hypertension, and obstructive sleep apnea).1,20,21,27 In the semaglutide group, approximately 70% of participants achieved a weight loss of at least 10%, and approximately 50% achieved a weight loss of at least 15%. Furthermore, one third of participants treated with semaglutide lost at least 20% of baseline weight, a reduction approaching that reported 1 to 3 years after bariatric surgery, particularly sleeve gastrectomy (approximately 20 to 30% weight loss).28-31 The magnitude of reduction in cardiometabolic risk is assumed to be proportional to the amount of weight lost with both approaches (i.e., pharmacotherapy or surgery).32 Analyses from the DXA substudy suggested that semaglutide led to greater reduction in fat mass than lean body mass, a finding consistent with previous findings with semaglutide (at a dose of 1.0 mg) in persons with obesity22 and in those with type 2 diabetes.33 The weight loss and improvements with respect to cardiometabolic risk factors with semaglutide reported here will be complemented by an ongoing cardiovascular outcomes trial in participants with overweight or obesity and established cardiovascular disease (the SELECT trial; ClinicalTrials.gov number, NCT03574597. opens in new tab). Liraglutide administered subcutaneously once daily is the only GLP-1 receptor agonist approved for weight management.3,19,34 Our trial showed greater mean placebo-corrected weight reductions with once-weekly 2.4-mg semaglutide plus lifestyle intervention (12.4%) than those reported with once-daily 3.0-mg liraglutide plus lifestyle intervention in the 56-week SCALE (Satiety and Clinical Adiposity — Liraglutide Evidence in Nondiabetic and Diabetic Individuals Obesity and Prediabetes) trial (4.5%).34,35 In addition, the weight-loss phase with semaglutide persisted longer than that reported with liraglutide35 and did not reach the nadir until week 60. However, these two studies differed in their participant population, which limits the robustness of between-study comparisons. At week 68, 31% of participants who received placebo had lost at least 5% of baseline body weight, with 12% and 5% having achieved reductions of at least 10% and at least 15%, respectively, findings that show good adherence to lifestyle interventions. Similar results were observed at week 56 in the SCALE Obesity and Prediabetes trial.35 Currently, approved antiobesity drugs require administration once, twice, or three times daily,3,19 and a once-weekly regimen may improve treatment adherence. The once-weekly 2.4-mg dose of semaglutide was chosen for the present study on the basis of pharmacokinetic modeling that suggested that the 2.4-mg weekly dose had a maximum steady-state concentration similar to a once-daily 0.4-mg dose investigated in a phase 2 dose-finding trial in participants with obesity.14 The results of our study with once-weekly semaglutide at a 2.4-mg dose are consistent with the results of the phase 2 study, which showed an 11.6% greater reduction in body weight with once-daily semaglutide at a dose of 0.4 mg than with placebo after 52 weeks of treatment.14 The safety of semaglutide was consistent with that reported in the phase 2 study with once-daily dosing in participants with obesity14 and in the trials of once-weekly subcutaneous semaglutide in persons with type 2 diabetes (involving more than 8000 participants receiving doses up to 1 mg),12 as well as with that reported for the GLP-1 receptor agonist class in general.13,36 As is typical of this drug class,13,37 transient, mild-to-moderate gastrointestinal disorders were the most frequently reported adverse events, and more participants in the semaglutide group than in the placebo group discontinued the assigned regimen after such events. Nausea was the most common gastrointestinal event, occurring primarily during the dose-escalation period, a finding similar to that reported with liraglutide at a dose of 3.0 mg.35 Gallbladder-related disorders, principally cholelithiasis, were more common in the semaglutide group, a finding consistent with previous reports for GLP-1 receptor agonists38,39 and with the known effects of rapid weight loss.40,41 The incidence of cholelithiasis with semaglutide was in line with that of liraglutide at a dose of 3.0 mg.35 No new safety concerns arose. Strengths of this trial included the large sample size and high rates of adherence to the treatment regimen and completion of the trial. Limitations included the preponderance of women and White participants, the relatively short duration of the trial, the exclusion of persons with type 2 diabetes, and the potential that participants who were enrolled may represent a subgroup with greater commitment to weight-loss efforts than the general population. Although the DXA data we report provide greater insight into the weight-loss effects of semaglutide, such assessments were performed in only a subpopulation of participants. Our trial showed that among adults with overweight or obesity (without diabetes), once-weekly subcutaneous semaglutide plus lifestyle intervention was associated with substantial, sustained, clinically relevant mean weight loss of 14.9%, with 86% of participants attaining at least 5% weight loss. Winter Chemical Peels-Skinmedica: 8 Tips for Post Chemical Peel Care If you’re a beauty junkie and/or skin care connoisseur, you’ve most likely heard of chemical peels. At our Skin Clinic in Oak Bluffs, they are one of our most request services. So let’s discover together the benefits as well as post-procedure care for best visible results. Chemical peels are an excellent way to rejuvenate the skin. By removing the outermost surface layer of skin, peels can help reduce signs of aging, discoloration, sun damage, and post-acne scarring. At the same time, the layer of skin underneath, a brighter and smoother-looking layer, is revealed. Chemical peels can vary in intensity. Depending on your skin's sensitivity, you may encounter side effects that you're not used to. Here’s exactly how to care for skin after a chemical peel to avoid discomfort, maintain optimal skin health and see visible results. How do you Care for your Skin After a Chemical Peel? Whether you use a clinical-grade overnight peel like the Skinmedica sensitive peel or you receive treatment from a skin clinic, there are several ways that you can minimize recovery time and get your skin back to feeling its best. #1 Don't Pick at Your SkinThe number one rule of chemical peel healing is to let your skin peel on its own. Though it may be tempting to help speed up the process, removing any dry, dead skin by rubbing or peeling it can damage the newly exposed layer of your skin. Instead, allow your skin to peel on its own and wait until it has fully healed to use any exfoliator. #2 Wait to Resume Your Skincare RegimenRefrain from using too many products on your face. While moisturizers and sunscreen are advised, putting too much product on your healing skin could lengthen your recovery time and irritate it in the process. Once your skin feels fully recovered, resume your usual skincare routine. #3 Wash your Face with Cool WaterWhen washing your face after a peel, wash it with cool or warm water. Using hot water can irritate or damage the treated area of skin and cause further irritation. Using cool water will not only feel better on your skin, but it can also help calm irritation and provide relief. Sensitive skin cleansers like Angela Caglia's oil will help cleanse and soothe your face without causing tightness or irritation. #4 Avoid Heavy WorkoutsAfter your chemical peel, you'll want to avoid strenuous workouts for up to four days. Heavy workouts can increase blood circulation to the face and intensify your post-peel symptoms. In addition to exercising, you should also avoid saunas and steam rooms directly after a chemical peel. #5 Keep Skin MoisturizedAfter a chemical peel, the natural protective barrier of your skin will be a bit weaker than usual. While your skin is repairing itself, it's important to reinforce that barrier by applying a lightweight moisturizer like Anglea Caglia's Souffle. Expertly formulated to provide long-lasting relief, the recovery cream will help visibly reduce redness while improving your skin’s natural protective barrier [1]. Staying hydrated by drinking at least eight glasses of water a day can help hydrate your skin from the inside out and avoid dehydration. #6 Don't Over-ExfoliateChemical peels are exfoliants themselves, which means you won't have to use a separate exfoliant within the first week of getting a peel. Even light exfoliators like scrubs, brushes, and cleansers can be harsh on your skin and cause redness and sensitivity. Before using an at-home exfoliator, give your skin time to recover and wait until it feels fully healed. #7 Apply Sunscreen RegularlyAfter getting a chemical peel, your skin will be more sensitive than usual. Because of this, it’s important to incorporate skincare products with SPF as part of your post-treatment aftercare. While harsh UV rays can damage your skin at any time, without its natural protective barrier, they are even more damaging after a peel [2]. Our Skin Health Experts recommend avoiding direct sun exposure and regularly applying sunscreen with SPF 30 or more. Using sun protection like Elta's is essential even if you're not in direct sunlight, as skin damage can occur from UV rays that enter the house through windows, doors, and shaded areas. #8 Make Time for Self-CareA chemical peel is a great option for maintaining healthy-looking skin. While your skin is recovering, be sure to make time for self-care, and don't worry about your skin for a few days. Reading a book, getting a manicure, or enjoying a bubble bath will help soothe your senses and allow your skin to heal in its own time. When applying any skincare treatment, it’s important to remember that everyone’s skin reacts differently. Whether you experience a few or many of the symptoms on this list, taking care of your skin post chemical peel will help transform your skin texture and visibly reduce dark spots, lines, and wrinkles. Sources: 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849435/ 2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773941/ Nov 2022-exclusive Angela Caglia products-vegan free and LA esthetician for 27 years.. Love her natural easy to use products that make a real difference. Buy products on Martha's Vineyard Island at Belljuve. Celebrity Esthetician | Anti-Aging Clean Clinical Skincare – Angela Caglia Skincare Oct 2022-My new favorite Skin Producct Angela Caglia-simple and really excellent Copy and paste to see line:https://cdn4.fireworktv.com/medias/2022/9/25/1664137427-jmczxvho/watermarked/540/BiggestNamesSouffle.mp4 July 2, 2019 Beauty Microneedling And BotoxThis post continues to be my most searched blog post month after month, so I thought I would add to it, as I just got my 3rd Microneedling session at Allure Rejuvenation Center. After not being able to get any treatments for over 6 months, let alone leave my house really, I appreciated every second and was so excited to see that glow in my skin a few days later. If you are new to Microneedling, scroll down to read about the whole procedure in detail. I also go into Microneedling with Dysport and why it has been my absolute holy grail of procedures. Now let me speak to this latest session a bit. I had not gotten Botox, or Dysport rather (what I have been using, in place of Botox at Allure) since December, nine month ago, so my skin was in let’s call it “its most natural state”. This made me super excited for the third Microneedling session with Dysport, because I would truly see if the Dysport, applied just at the surface of the skin, really makes a difference with Microneedling. And let me report, that it yes ma’am it sure does! On day two my skin had it’s usual slight sandpaper feel, which I made sure to apply extra moisturize to and keep it protected from the sun. Then, around day 4 is when I really saw a difference. I woke up with a glow and my skin looking and feeling more taught and just plain more youthful. It really was noticeable. Since the Dysport is dripped onto the skin (not injected), then pushed slightly under the surface with the Microneedling pen, it works in the same way as when injected but in a way more subtle way. So, everything still moves, your skin just looks more youthful in a subtle way. If you are considering Microneedling, I definitely recommend adding on Dysport or Botox (again, same thing just different brand names) Allure Rejuvenation Center was one of the first to start offering this treatment and I’m very glad I tried it out! Never going back. Before I go, a quick note on Dysport vs. Botox. As I mentioned, they are very similar, like two brands that makes the same type of product. Think Pepsi vs Coca Cola. You may have a preference toward one over the other. Dysport is a bit less expensive and metabolizes slower in some people, aka lasts longer. I would recommend trying it once and seeing how it compares to Botox for you, and see which one is more your cup of tea. Some people metabolize both at the same rate, so you may not see a huge difference, but I’m always a fan of trying out multiple options to see what works best for me. I also noticed that I did not bruise at all with Dysport, when I got my last set of injections a few weeks ago, whereas I do always get at least one or two little bruises with Botox. Not sure if that was just coincidence, but definitely adding to the Dysport ‘pro’ list. Not going to lie guys, one of the biggest highlight of quarantine being over, is getting out for a few beauty treatments! I’ll be sure to document what I try out next at Allure here. They are offering some amazing new things that are kind of blowing my mind. To be continued! {ORIGINAL POST – JULY 2019} From the very first day I walked into Sheri’s Allure Rejuvenation Center office for a consultation visit, we started discussing Microneedling. I have done other procedures with Allure in the past year (seen HERE) and since seeing this procedure pick up speed on the popular meter I have been dying to try it for myself. I love to nerd out on a good skincare treatment and the innovative twist Sheri adds to her technique had me counting down the days until our first session. But what is Microneedling anyway? Microneedling is a process of dragging an electrical pen-like tool with tiny needles at the head along the face, puncturing the surface. (thus, the name) The idea is to create micro injuries in the skin, as well as get products (a combination of serums applied to the skin) deep into the skin. The healing process of the tiny injuries then helps promote the production of collagen which in turn helps to minimize wrinkles, give the skin a more supple, thicker appearance and help with pigmentation issues. (YES, to all of this please!) Does it hurt? In doing my research prior to my first treatment I saw that some aestheticians choose to do Microneedling with no numbing cream. Yikes! I had the pleasure of having a 20-minute Adele listening session while Sheri applied a generous dose all over my face and let it activate. We then started on my forehead which is (in my opinion) the only painful part. This is because there is no fat there, so it truly feels like you are having needles dragged along your face. Joy! I imagine this is what getting a tattoo feels like. I let out my breath as we finished the 3 passes on the forehead and moved on to kinder territory of my cheeks and chin. Easy breezy from here on out! The numbing cream is key girls! I can’t imagine doing this procedure without it. What is Microneedling with Botox? If you have heard of “Botox Stamping” or the “Botox Facial”, this is a take on that and a technique that Sheri swears by. Instead of injecting Botox with a needle, she drips it directly onto the skin (along with the mix of SkinCeuticals serums) and then runs the microneedle pen over it 3 times. The whole cocktail, Botox included, gets pushed in at the dermal level, penetrating the skin but not getting into the muscular level like Botox would when injected. This part is what made me send Sheri a text on day 5 post my first month’s treatment with a “Holy S*h%t!! My skin looks amazing!” I woke up, went to wash my face and literally gasped at the more youthful face looking back at me. The data is mixed on this, as it is still a new technique, but I’ll just say, speaking for my own results, huge fan! Is there downtime after? After the procedure is done, Sheri lathers on the rest of the serum as well as SkinCeuticals SPF 50 and I put on my giant hat to head to the car. My face feels like it is on fire as the numbing cream wears off, but this only lasts for about an hour. When I get home, I feel a slight burning sensation which only gets worse when I go to wash my face at night. Then there is a period of about 20 minutes when my skin feels super raw, before it returns to normal. I highly recommend doing this treatment on a Friday if you’ve got a 9-5. While there is not necessarily a downtime period, your skin does feel very raw and exposed for the next 24 hours or so, and the procedure is the most effective if you ‘lather yourself up’ with as much moisture during that time as possible. Think of it this way, your skin is more ‘open’ during that time. Would you rather apply the good stuff like THIS and let it do its magic while you’re healing, or drown your skin in foundation, trying to hide redness from your office mates? What is the post care regiment? Aside from keeping your skin moisturized, I’ve found that taking Arnica tablets before and after treatment really cuts the healing time. (I start 2 days before) This was another Sheri gem, so I can take zero credit. SPF is also a must if you plan on going outside. This one comes highly recommended and has been my go-to. Lastly, do a sheet mask at the end of the day, post treatment. It really helps to calm the skin and absorb more of ALL the good stuff. This one was magical! How often should you do it? Microneedling is safe to do every 30 days. I am doing a 4-round treatment at Allure Rejuvenation Centerand will continue to add info here as I go through the whole process. Send any questions my way via comments or email! (veronica@lombardandfifth.com) I am currently on day 3 post my second treatment. My skin still has a bit of a fine sandpaper feel, which goes away (at least for me around day 4). Can’t wait to wake up and say ‘Hello gorgeous!’ on day 5 again! How does it take for Retinols to Anti-wrinkle Skin Here are some facts: Many people ask how to get rid of wrinkles fast- and the answer is always – RETINOIDS. But how long do retinoids take to improve wrinkles? Before we discuss how long it takes to see results from retinol, let's discuss nomenclature. Retinol is a type of retinoid.1 There are prescription and cosmetic retinoids. Retinol is found in cosmetic products, adapalene is in over-the-counter products while tretinoin, adapalene, tazarotene and trifarotene are found in prescription products. The only retinoids FDA approved to treat wrinkles are tretinoin and tazarotene. However, studies have shown that retinol is effective on wrinkles.2 This blog will review the peer-reviewed evidence-based data on using retinol and retinoids for wrinkle. In a study3 comparing tretinoin 0.1% and retinol 0.1%, both retinoids showed skin improvement under the microscope at 4 weeks. However, it usually takes at least 12- 24 weeks to see skin changes without a microscope. Studies have shown that retinol improves wrinkles. Retinol 0.1% was shown to improve crow’s feet lines by 44% at 52 weeks (one year).4 How fast wrinkles improve depends on the potency, frequency and amount of retinoid used. You do not want to start a strong retinoid too quickly because it can lead to retinoid side effects. Remember that prescription retinoids are stronger than retinol so you will see results faster with prescription retinoids. However, we advise you to first begin a low-strength retinol and work your way up slowly to a stronger retinol and then convert over to a prescription strength retinoid. Click here to see how to use retinoids. In 2001, a study compared 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams and tretinoin 0.05% cream.5 These were applied every night for 24 weeks. All of the percentages of tazarotene and the 0.05% tretinoin improved fine wrinkles and evened skin tone. Tazarotene 0.1% worked the best at 8, 12, and 20 weeks but had a higher rate of side effects. However, by 24 weeks, tretinoin 0.05% and tazarotene 0.1% had similar efficacy. This study shows that wrinkles improve the fastest with tazarotene 0.1% as compared to tretinoin 0.05% and lower doses of tazarotene. How Fast Does Tretinoin Improve Wrinkles?Most people who use tretinoin see improvement of wrinkles by 24 weeks.6 A higher percent of tretinoin (0.1%) has faster improvement of wrinkles as compared to a tretinoin strength of 0.05%. Higher-strength tretinoin improves wrinkles faster than low doses do, however, with time, they both improve wrinkles the same. A 1995 study compared wrinkle improvement placebo cream vs tretinoin 0.025% cream vs tretinoin 0.1%.7 As expected, the 0.025% cream was associated with fewer side effects than the 0.1% tretinoin. At 48 weeks, the improvement of wrinkles was the same (there was no statistical difference) for both doses of tretinoin- showing that lower strength retinoids will have the same improvement as the higher strength ones with time. Do Stronger Retinoids Improve Wrinkles Faster?Higher percentages of retinoids improve wrinkles faster, so if you want to get rid of wrinkles quickly, a stronger retinoid is the way to go but be prepared to have more side effects. Many studies have shown that weaker retinoids take longer to see results, but have fewer side effects.8 One study of tretinoin emollient cream for 48 weeks compared two groups: the first group used tretinoin 0.05% and the other group used tretinoin 0.01%. At 24 weeks, more improvement was seen in the 0.05% group as expected because this was a more potent form of retinoid. The 0.01% group showed less improvement at 24 weeks but continued to improve from weeks 24- 48. By 48 weeks, the lower dose group still did not achieve the levels of improvement observed with the stronger 0.05% formulation. These results demonstrate that higher doses yield a faster and better response at 48 weeks, but lower doses do cause improvement in wrinkles and skin appearance. How Fast Does Tazarotene Improve Wrinkles?Studies have shown that tazarotene 0.1% is the most effective antiaging retinoid. It was approved by the FDA in 19979 to improve the appearance of fine facial wrinkles and uneven skin tone. Results may be seen as early as 8 weeks.10 One study of tazarotene 0.1% gel ( compared to placebo) used on the arms showed improvement of wrinkles and skin texture at 12 weeks.11 A summary of research trials using tazarotene for wrinkles can be found in this reference.12 In summary- the higher a retinoid percentage is- the faster wrinkles and fine lines will go away but more side effects will be seen. Retinoid side effects can lead to inflammation and pigmentation. Inflammation is a cause of skin aging and an uneven skin tone is undesirable. For this reason- we recommend starting with a low strength retinoid and slowly working your way up to the strongest retinoid that you can tolerate without getting skin inflammation. References
© 2006 - 2022 Skin Type Solutions Importance of Daily Skin Care Regime: Good skin isn’t merely a result of good genes; your daily habits have a significant influence on what you see in the mirror. Depending on which product reviews you read or whose experts you visit, there are a surprising amount of ideas on anything from how to moisturize to how to protect oneself from UV radiation. It is a matter of personal preference when it comes to skincare routines. Here are a few things to keep in mind while trying to make sense of what you should be using in your Skin Care Routine. The Order Matters When you use your skin care products in the correct order, your skin will reap the full benefits of each one. The order in which you apply your skincare essentials is critical. The skin’s role is to keep things out, but many of the skincare products we use contain substances we don’t want in there. Even when correctly made and administered, just a tiny amount of these essential chemicals can penetrate the skin. You won’t get the most pleasing effects from your skin care regimen if you don’t use items in the proper order. Understanding the basics Apart from the order in which you apply your Skin Care Routine, some experts believe it’s also important to consider how long your skin takes to absorb them. This isn’t always achievable because most of us are in a hurry to get somewhere (or get to bed). All it takes is to maintain a modest skincare routine. Many products state that you should wait five to thirty minutes before proceeding to the next step to ensure proper absorption. But if you think about it, that’s a pretty long time to wait, and eventually, you won’t do it. If you’re doing a lot of steps, take a minute to let each product react with the skin. Pay attention to your skin. Keep in mind that your skin is unique and that no one else has it. Whatever the professionals advise, it’s crucial to identify what works for you and treat your skin gently. The Art of Layering So, you’re wondering which product goes on top of which. Apply your products from thinnest to thickest consistency or liquid to cream as a simple rule of thumb. Think thin-to-thick in general, but start with the products with the most vital elements to infiltrate the skin, such as antioxidants in serums. You can finish it with the products that need to sit on top of the skin, like emollients and humectants in moisturizers. Your Morning Skin Care RoutineIt is important to note that the purpose of the morning routine is to shield yourself from the sun, pollution, and the elements. As a result, you must save your peel pads and therapy products, such as retinol, for the evening. 1. Cleanse Start your day by washing your face with warm water on your face or, if necessary, washing with a gentle face cleanser tailored for your skin type. 2. Tone Most individuals avoid toners, partly due to the misconception that toners are harsh and irritate the skin. Fortunately, that is no longer the case. While the latest toners do not literally “shrink” pores, they can work as a delivery system for antioxidants, vitamin-B derivatives, and even toning acids. Furthermore, because each type of toner is designed to address a specific skin issue, it’s critical to use the correct one for your problem. But other dermatologists believe that there’s no need to start using a toner if you’ve never used one before and your skin is healthy. Toners were intended to help reset the skin’s pH when it becomes too basic from harsh cleansers. Toners become no longer necessary for others because there are face cleansers that are so well balanced. However, if you have a favorite toner, there’s no harm in sticking with it. 3. SerumsSerums are highly concentrated, nutrient-dense therapies that target specific issues. Thus they should be applied as near to the skin as possible. There are a variety of serums on the market today, but you can use antioxidant serums for daytime use. Antioxidant serums provide several benefits, including reducing inflammation and neutralizing the damage caused by UV radiation and environmental contaminants. 4. Moisturize Even if you have oily skin, you should use a moisturizer. The body has its natural lubricating system of glands that secrete oil or sebum. But to maintain a protective covering against harsh outside conditions and infections. According to most experts, the ideal time to apply a moisturizer is while the skin is still damp. The sooner you finish using your serum and treatment, the sooner you can lock in much-needed hydration with your moisturizer. 5. Sunscreen Suppose you’re using a physical or mineral sunscreen that works by physically blocking UV rays. In that case, it should be the last step in your daytime skincare routine. When applying chemical sunscreen, this procedure becomes more difficult. Chemical sunscreens must be absorbed into the skin to be effective; therefore, applying after your moisturizer will delay that. However, because the skin is coated with chemical sunscreen, your moisturizer will not perform as well if you use your chemical sunscreen before your moisturizer. Using a physical sunscreen with zinc and applying it after your moisturizer is recommended to avoid this. Zinc is safe, effective, and gives the broadest UVA and UVB protection. Those who like chemical sunscreens should look for a formula that also has moisturizing properties, so they can obtain their daily hydration while still protecting their skin. Your Night Time Skin Care Routine Because your skin restores itself at night, your nighttime regimen should treat and provide what your skin needs. Exfoliate if your skin is looking dull. Hydrate and protect it if it’s irritating. Here’s how to use skincare products in the optimal order to get the most out of them: 1. Double the Cleansing Some experts advocate removing your makeup first by using a specialized makeup remover before washing your face with a gentle cleanser to get rid of the day’s filth, dirt, oil, and cosmetics. Better yet, consider double cleansing, which entails first dissolving your makeup with cleansing oil and then rinsing your face with your regular cleanser. 2. Using Toners, Boosters, and EssenceIf you’re using a toner, use it the same way you would in the morning. Some people like to layer different skincare boosters at night, such as mists, beauty waters, essence, or hydrating serums. These serums are infused with various active ingredients, but the main goal is to hydrate and nourish the skin. Because these are light, almost water-like compositions, use them as a toner after washing your face. If you’re using both, apply toner first, then essence. Toner is used to clean the skin, whereas essence is used to administer treatment. The exact instructions apply when using numerous boosters: start with the thinnest and work your way up. 3. Eye Cream Eye creams help protect your delicate eye area from other skincare products in addition to treating crow’s feet and dark circles. Typically, you’d want to apply your eye cream before your treatments to protect your eye area from potent substances that could create irritation. 4. The Treatments Sleep is where our skin, like the rest of our bodies, accomplishes the majority of its mending, restoring, and rejuvenating. Most targeted skincare treatments, such as prescription medications (tretinoin, acne, and rosacea creams), retinol creams, exfoliating treatments (peel pads and masks), and anti-aging serums (loaded with peptides, growth factors, and other biologically active substances), are best used at night. Rather than layering all of your treatment serums and creams, selecting your nightly treatment based on your skin’s current needs is recommended. Too many processes increase the danger of discomfort and diminish the likelihood of achieving the intended effect. Choose your evening treatment based on what your skin requires that evening, not on what you have in your medicine cabinet. Some nights, all you have to do is wash, moisturize, and go to bed. There’s always tomorrow to lavish extra attention on your skin. 5. Night Cream or Moisturizers Some people apply the same moisturizer at night and during the day. Night moisturizers or night creams, on the other hand, are typically thicker and heavier and are intended to be absorbed over several hours. Moisturizer creates a protective covering on the skin to reduce water evaporation while you sleep. Keeping the skin hydrated is essential for healing and maintaining good skin. It should be your last step if you’re using the appropriate moisturizer because nothing will get through it. If your skin is dehydrated, apply a face oil before applying your night cream. Final Thoughts Keep in mind that how products perform is influenced by your skin type. Using the incorrect natural product might result in breakouts, pimples, and redness. It’s critical to determine your skin type and personalize your skincare accordingly. Skincare routine accordingly. You can also take notes on product ingredients to determine if any of them produce allergic reactions on your skin.(Article Compliments Audrey Rose Aesthetic Institute) Benefits of lip fillers: Natural Hyaluronic Acid Fillers:
In Your 30s: "In general, for prophylaxis, if someone is taking care of their skin I recommend Xeomin®/Botox® starting in their thirties. Depending on the level of sun damage and the amount of muscle movement, all of these factors play into the decision at which age to start using Botox. So, if there was a strong frown, it may be appropriate to start as early as 20. If not so much, 30 — at the latest 35." —Ava Shamban, a Beverly Hills-based dermatologist and founder of SkinxFive. In Your 40s: "The most appropriate age to start Xeomin®/Botox® will depend on the skin color and the type of lifestyle (more versus less sun). In general, Caucasian women (who were not lifeguards) usually do best when they start Xeomin®/Botox® between 30 and 40. If they were a lifeguard, maybe 25. For darker skin tones, the appropriate age to start Botox tends a bit higher, more like 40 to 45, but it will also depend on the circumstances. If someone has gotten a lot of sun exposure or their lifestyle is harder on the skin (i.e. smoker, lives in high altitudes, etc.), then it could be earlier. The chronologic age to start Xeomin®/Botox® is often irrelevant. It is more important to look at the dynamic wrinkles themselves. When the movement wrinkles on the upper part of the face start to linger after the movement has stopped — like seeing crow's feet but not smiling — that's the best time to start treatments." — |
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